  {"id":47764,"date":"2016-07-13T10:07:03","date_gmt":"2016-07-13T20:07:03","guid":{"rendered":"http:\/\/www.hawaii.edu\/news\/?p=47764"},"modified":"2020-03-13T15:45:25","modified_gmt":"2020-03-14T01:45:25","slug":"alzheimers-gene-may-show-effects-on-brain-starting-in-childhood","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2016\/07\/13\/alzheimers-gene-may-show-effects-on-brain-starting-in-childhood\/","title":{"rendered":"Alzheimer\u2019s gene may show effects on brain starting in childhood"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> &lt; 1<\/span> <span class=\"rt-label rt-postfix\">minute<\/span><\/span><figure id=\"attachment_47787\" aria-describedby=\"caption-attachment-47787\" style=\"width: 630px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" src=\"http:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2016\/07\/manoa-jabsom-chang-linda.jpg\" alt=\"\" width=\"620\" height=\"388\" class=\"size-full wp-image-47787\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2016\/07\/manoa-jabsom-chang-linda.jpg 620w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2016\/07\/manoa-jabsom-chang-linda-260x163.jpg 260w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2016\/07\/manoa-jabsom-chang-linda-480x300.jpg 480w\" sizes=\"auto, (max-width: 620px) 100vw, 620px\" \/><figcaption id=\"caption-attachment-47787\" class=\"wp-caption-text\">John A. Burns School of Medicine&#8217;s Linda Chang in front of a brain scan of an 8-year-old child<\/figcaption><\/figure>\n<p class=\"clear-photo\">A gene associated with Alzheimer&#8217;s disease and recovery after brain injury may show its effects on the brain and thinking skills as early as childhood, according to <a href=\"http:\/\/www.neurology.org\/content\/early\/2016\/07\/13\/WNL.0000000000002939.short\">a study published<\/a> in the July 13, 2016, online issue of <em>Neurology<\/em>, the medical journal of the <a href=\"https:\/\/www.aan.com\/\">American Academy of Neurology<\/a>.<\/p>\n<p>Prior studies showed that people with the epsilon(&#949;)4 variant of the apolipoprotein-E gene are more likely to develop Alzheimer&#8217;s disease than people with the other two variants of the gene, &#949;2 and &#949;3.<\/p>\n<p>&ldquo;Studying these genes in young children may ultimately give us early indications of who may be at risk for dementia in the future and possibly even help us develop ways to prevent the disease from occurring or to delay the start of the disease,&rdquo; said study author University of <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> at M&#257;noa <a href=\"http:\/\/jabsom.hawaii.edu\/\">John A. Burns School of Medicine<\/a> Professor <strong>Linda Chang<\/strong>.<\/p>\n<p>Read more about the Alzheimer&#8217;s study at the <a href=\"http:\/\/jabsom.hawaii.edu\/research-led-by-dr-linda-chang-alzheimers-gene-may-show-effects-on-brain-starting-in-childhood\/\"><abbr title=\"John A. Burns School of Medicine\">JABSOM<\/abbr> website<\/a>.<\/p>\n<p><em>&#8212;By Tina Shelton<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A study by <abbr title=\"University of Hawaii\">UH<\/abbr> M&#257;noa&#8217;s Linda Chang shows people with a specific variant of the apolipoprotein-E gene are more likely to develop Alzheimer&#8217;s disease.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[972,165,31,9],"class_list":["post-47764","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-alzheimers-disease","tag-health","tag-john-a-burns-school-of-medicine","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/47764","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=47764"}],"version-history":[{"count":21,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/47764\/revisions"}],"predecessor-version":[{"id":113764,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/47764\/revisions\/113764"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=47764"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=47764"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=47764"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}