  {"id":184636,"date":"2023-10-05T13:12:47","date_gmt":"2023-10-05T23:12:47","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=184636"},"modified":"2023-10-05T14:16:30","modified_gmt":"2023-10-06T00:16:30","slug":"car-tcell-cancer-therapy-available","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2023\/10\/05\/car-tcell-cancer-therapy-available\/","title":{"rendered":"Cutting-edge cancer therapy now available through <abbr>UH<\/abbr> partnership"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> 2<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><figure id=\"attachment_184644\" aria-describedby=\"caption-attachment-184644\" style=\"width: 676px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-patient.jpeg\" alt=\"doctor and patient wearing masks and speaking together\" width=\"676\" height=\"382\" class=\"size-full wp-image-184644\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-patient.jpeg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-patient-300x170.jpeg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-patient-130x73.jpeg 130w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-184644\" class=\"wp-caption-text\">Stephanie Si Lim meets with a patient. (Photo credit: Hawaii Pacific Health)<\/figcaption><\/figure>\n<p>A new type of immunotherapy treatment for cancer patients, Chimeric Antigen Receptor (<abbr>CAR<\/abbr>) T-cell therapy, was recently made available in <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> through a partnership between the <a href=\"http:\/\/www.uhcancercenter.org\">University of <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> Cancer Center<\/a> and <a href=\"https:\/\/www.hawaiipacifichealth.org\/\"><span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> Pacific Healt<\/a>h (<abbr>HPH<\/abbr>). <\/p>\n<p>This new treatment allows some of the sickest cancer patients to stay in Hawai\u2018i with family and friends for care instead of traveling to the mainland. <\/p>\n<figure id=\"attachment_184643\" aria-describedby=\"caption-attachment-184643\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-hph-doc-300x169.jpg\" alt=\"male and female doctor wearing masks\" width=\"300\" height=\"169\" class=\"size-medium wp-image-184643\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-hph-doc-300x169.jpg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-hph-doc-130x73.jpg 130w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/10\/manoa-cancer-center-si-lim-hph-doc.jpg 676w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-184643\" class=\"wp-caption-text\">Craig Boddy and Si Lim are physicians at <span aria-label=\"Kapiolani\">Kapi&#699;olani<\/span> Hospital for Women &#38; Children. (Photo credit: Hawaii Pacific Health)<\/figcaption><\/figure>\n<p>&ldquo;<abbr>CAR<\/abbr> T-cell therapy is a very innovative and specialized type of cellular immunotherapy where we&#8217;re able to use a patient\u2019s own immune cells, genetically modify them, and use those modified cells to fight cancer,&rdquo; said <abbr>UH<\/abbr> Cancer Center Assistant Researcher Stephanie Si Lim, who is a pediatric hematologist\/oncologist at <span aria-label=\"Kapiolani\">Kapi&#699;olani<\/span> Medical Center for Women &#38; Children and medical director of the cellular immunotherapy program at <abbr>HPH<\/abbr>. &ldquo;It is very different from traditional chemotherapy because it targets cancer cells with more precision.&rdquo; <\/p>\n<p>Lim has spent the last two-and-a-half years <a href=\"https:\/\/www.hawaii.edu\/news\/2022\/07\/26\/car-t-cell-therapy-initiative\/\">building the cellular immunotherapy program<\/a> at the <abbr>UH<\/abbr> Cancer Center and <abbr>HPH<\/abbr>. <abbr>CAR<\/abbr> T-cell therapy is now offered to children with B-cell acute lymphoblastic leukemia and adults with B-cell lymphoma and multiple myeloma. Here are a few milestones of this breakthrough program for the state:<\/p>\n<ul>\n<li>March 26, 2021: The first <abbr>CAR<\/abbr> T-cell clinical trial opened for qualifying pediatric patients at <span aria-label=\"Kapiolani\">Kapi&#699;olani<\/span> Medical Center for Women &#38; Children.<\/li>\n<li>May 22, 2023: The first Food and Drug Administration (<abbr>FDA<\/abbr>)-approved <abbr>CAR<\/abbr> T-cell therapy is available for use for pediatric and adult patients in <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span>.<\/li>\n<li>August 22, 2023: The first adult patient is infused with <abbr>CAR<\/abbr> T-cells at Straub Medical Center.<br \/>\nOctober 1, 2023: Adult patient who was infused with <abbr>CAR<\/abbr> T-cells remains in remission despite having had multiple relapsed lymphoma prior to receiving <abbr>CAR<\/abbr> T-cell therapy.<\/li>\n<\/ul>\n<p>&ldquo;Through <abbr>HPH<\/abbr> and the <abbr>UH<\/abbr> Cancer Center\u2019s joint efforts, we are excited to offer this important and lifesaving therapy to patients with difficult-to-treat cancers,&rdquo; Lim said. &ldquo;We look forward to our ongoing collaboration to expand the availability of groundbreaking <abbr>FDA<\/abbr>-approved oncology products and clinical trials for our community here in <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span>.&rdquo;<\/p>\n<p>Read more on the <a href=\"https:\/\/www.uhcancercenter.org\/about-us\/newsroom\/1024-cutting-edge-cancer-therapy-now-available-through-uh-cancer-center-partnership\"><abbr>UH<\/abbr> Cancer Center website<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This new treatment allows some of the sickest cancer patients to stay in Hawai\u2018i for care instead of traveling to the 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