  {"id":176600,"date":"2023-04-28T08:00:43","date_gmt":"2023-04-28T18:00:43","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=176600"},"modified":"2023-04-28T09:07:07","modified_gmt":"2023-04-28T19:07:07","slug":"crispr-comes-to-uh-gets-149k-boost","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2023\/04\/28\/crispr-comes-to-uh-gets-149k-boost\/","title":{"rendered":"Genetic editing tech <abbr>CRISPR<abbr> comes to <abbr>UH<\/abbr>, gets $149<abbr>K<\/abbr> boost"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> 2<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><figure id=\"attachment_176597\" aria-describedby=\"caption-attachment-176597\" style=\"width: 676px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-1.jpg\" alt=\"students sitting around teacher\" width=\"676\" height=\"381\" class=\"size-full wp-image-176597\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-1.jpg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-1-300x169.jpg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-1-130x73.jpg 130w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-176597\" class=\"wp-caption-text\">Students learning how to perform digital <abbr title=\"Polymerase chain reaction\">PCR<\/abbr> to analyze copy numbers of transformants<\/figcaption><\/figure>\n<p>University of <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> at M\u0101noa Assistant Professor <strong>Zhi-Yan &ldquo;Rock&rdquo; Du<\/strong> from the Department of Molecular Biosciences and Bioengineering (<abbr>MBBE<\/abbr>) has received a <a href=\"https:\/\/cris.nifa.usda.gov\/cgi-bin\/starfinder\/0?path=fastlink1.txt&#038;id=anon&#038;pass=&#038;search=R=97551&#038;format=WEBLINK\">$149,000 grant<\/a> from the <abbr title=\"United States Department of Agriculture\">USDA<\/abbr>\u2019s National Institute of Food and Agriculture to jumpstart a project that will introduce the <abbr title=\"University of Hawaii\">UH<\/abbr> System to <abbr title=\"Clustered Regularly Interspaced Short Palindromic Repeats\">CRISPR<\/abbr>, the basis of genetic editing technology.<\/p>\n<p>Motivated to educate <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span>\u2019s current and future workforce in this cutting-edge technology&#8212;and to better represent Native Hawaiians and other Pacific Islanders in science and technology disciplines&#8212;Du has initiated the first official <abbr>CRISPR<\/abbr> laboratory course at <abbr>UH<\/abbr> M\u0101noa, in addition to <abbr>CRISPR<\/abbr> workshops for baccalaureate and two-year postsecondary students within the <abbr>UH<\/abbr> System.<\/p>\n<figure id=\"attachment_176594\" aria-describedby=\"caption-attachment-176594\" style=\"width: 250px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-du.jpg\" alt=\"Zhi-Yan \u201cRock\u201d Du\" width=\"250\" height=\"350\" class=\"size-full wp-image-176594\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-du.jpg 250w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-du-214x300.jpg 214w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-du-93x130.jpg 93w\" sizes=\"auto, (max-width: 250px) 100vw, 250px\" \/><figcaption id=\"caption-attachment-176594\" class=\"wp-caption-text\">Zhi-Yan &ldquo;Rock&rdquo; Du<\/figcaption><\/figure>\n<p>&ldquo;This education project will address the educational disparities and needs of curriculum development, instructional delivery systems and expand student career opportunities,&rdquo; said Du. &ldquo;The long-term goal of this project is to develop agricultural and science literacy in <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> by building competencies in molecular biology, genetics, biotechnology, agricultural science and science communication.&rdquo;<\/p>\n<p>Du and his graduate students and teaching assistants conducted an <abbr>MBBE<\/abbr>\/<abbr title=\"biology\">BIOL<\/abbr> 401Lab Molecular Biotechnology Lab-Gene Editing by <abbr>CRISPR<\/abbr>\/<abbr title=\"CRISPR associated\">Cas9<\/abbr> in spring 2023 and have also planned workshops in summer and fall, with the first workshop to launch in July 2023. Students will also utilize materials such as tropical maize from a <a href=\"https:\/\/www.hawaii.edu\/news\/2021\/09\/17\/improve-maize-breeding-food-production\/\">current research project<\/a> for this new education opportunity.<\/p>\n<h2><abbr>CRISPR<\/abbr> for the future, food of <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span><\/h2>\n<p>In the past decade, <abbr>CRISPR<\/abbr> genetic engineering tools have become an essential technology in numerous industries, including food and agriculture, drug development and therapy, as well as ongoing scientific research; however, Du said that <abbr>CRISPR<\/abbr> systems are &ldquo;not well understood in the general community, leading to fears and misunderstandings about genetic engineering and an overall anti-science outlook.&rdquo;<\/p>\n<p>&ldquo;<span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span> is heavily dependent on food imports,&rdquo; said Du. &ldquo;It\u2019s urgent to simulate local agriculture and workforce development. The grant will promote the education of college students on novel non-transgenic genome editing technologies, such as <abbr>CRISPR<\/abbr>\/<abbr>Cas<\/abbr> <abbr>RNP<\/abbr> (ribonucleoprotein) with gene gun\/particle bombardment methods. Students will learn and practice the new genome-editing technologies. We hope to engage more students from <abbr>UH<\/abbr> M\u0101noa and other campuses, including community colleges, in food and agricultural careers for our future food security and quality.&rdquo;<\/p>\n<p><a href=\"https:\/\/cms.ctahr.hawaii.edu\/NewsLetter\/ArtMID\/52574\/ArticleID\/2699\/CRISPR-Comes-to-UH\">Read more at the <abbr title=\"College of Tropical Agriculture and Human Resources\">CTAHR<\/abbr> website.<\/a><\/p>\n<figure id=\"attachment_176596\" aria-describedby=\"caption-attachment-176596\" style=\"width: 676px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-2.jpg\" alt=\"three females\" width=\"676\" height=\"381\" class=\"size-full wp-image-176596\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-2.jpg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-2-300x169.jpg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2023\/04\/manoa-ctahr-mbbe-crispr-2-130x73.jpg 130w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-176596\" class=\"wp-caption-text\">Graduate students in Du&#8217;s <abbr>MBBE<\/abbr> lab<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The education project will ultimately address educational disparities and develop agricultural and science literacy in <span aria-label=\"Hawaii\">Âé¶¹´«Ã½<\/span>.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[25],"tags":[222,212,951,1050,1466,1363,1314,1010,73,9],"class_list":["post-176600","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-academic-news","tag-agriculture","tag-college-of-tropical-agriculture-and-human-resilience","tag-food","tag-genetics","tag-manoa-enhancing-student-success","tag-manoa-research","tag-manoa-sustainability","tag-molecular-biosciences-and-bioengineering","tag-sustainability","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/176600","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=176600"}],"version-history":[{"count":5,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/176600\/revisions"}],"predecessor-version":[{"id":176613,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/176600\/revisions\/176613"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=176600"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=176600"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=176600"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}