{"id":162361,"date":"2022-07-26T15:45:46","date_gmt":"2022-07-27T01:45:46","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=162361"},"modified":"2022-07-26T13:48:49","modified_gmt":"2022-07-26T23:48:49","slug":"car-t-cell-therapy-initiative","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2022\/07\/26\/car-t-cell-therapy-initiative\/","title":{"rendered":"Broadening access to cancer fighting therapy led by UH<\/abbr> researcher"},"content":{"rendered":"Reading time: <\/span> 2<\/span> minutes<\/span><\/span>
\"Si
Stephanie Si Lim<\/figcaption><\/figure>\n

A therapy that helps modify a patient\u2019s T cells (a type of immune cell) to make them more capable of fighting cancer was recently brought to Â鶹´«Ã½<\/span> by Stephanie Si Lim<\/strong>, assistant professor at the University of Â鶹´«Ã½<\/span> Cancer Center<\/a> and pediatric hematologist oncologist at Kapiʻolani<\/span> Medical Center for Women & Children<\/a>. Chimeric Antigen Receptor T-cell therapy (CAR<\/abbr> T-cell therapy) can result in the development of life-saving treatments for cancers that are difficult to treat.<\/p>\n

\"si
Si Lim and a patient with B-cell acute lymphoblastic leukemia \u2013 Kapiʻolani<\/span> Medical Center for Women & Children.
<\/figcaption><\/figure>\n

Si Lim is leading the initiative at Kapiʻolani<\/span> Medical Center for Women & Children—part of Â鶹´«Ã½<\/span> Pacific Health—to build a broader cellular immunotherapy program. A key goal of the program is to introduce CAR<\/abbr> T-cell therapy to the medical community in Â鶹´«Ã½<\/span> in the form of clinical trials and U.S.<\/abbr> FDA<\/abbr> (Food and Drug Administration) approved products. This will ensure that patients have access to the best available treatments for cancer.<\/p>\n

CAR<\/abbr> T-cell therapy is now available to children and young adults with non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia, and will soon be available to adult patients. <\/p>\n

The first CAR<\/abbr> T-cell clinical trial opened on May 14, 2022, at Kapiʻolani<\/span> Medical Center for Women & Children, leveraging the infrastructure and expertise of the hospital\u2019s stem cell transplant and clinical research programs. Moving forward, all patients living in Â鶹´«Ã½<\/span>, including the neighbor islands who qualify for this clinical trial, will be able to receive treatment on Oʻahu<\/span> without having to travel to the continental U.S.<\/abbr><\/p>\n

Si Lim said, “We are so excited to be able to offer CAR<\/abbr> T-cell therapy to our patients here in Â鶹´«Ã½<\/span>. This is a momentous step for our medical community as we continue to strive to offer the best and most cutting-edge therapies to patients in need.”<\/p>\n

Currently, CAR<\/abbr> T-cell therapy is proven to be particularly effective against B-cell malignancies and multiple myeloma\u2014both common forms of cancer in adults and pediatric populations in Â鶹´«Ã½<\/span>. Over the next few years, it is expected that new FDA<\/abbr>-approved CAR<\/abbr> T-cell treatments will also be available for other cancers in the state, including breast and prostate.<\/p>\n","protected":false},"excerpt":{"rendered":"

The effort can result in the development of life-saving treatments for cancers that are difficult to treat.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[218,1467,1363,169,9],"class_list":["post-162361","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-cancer","tag-manoa-excellence-in-research","tag-manoa-research","tag-uh-cancer-center","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/162361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=162361"}],"version-history":[{"count":10,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/162361\/revisions"}],"predecessor-version":[{"id":162520,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/162361\/revisions\/162520"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=162361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=162361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=162361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}