{"id":104559,"date":"2019-10-09T14:28:19","date_gmt":"2019-10-10T00:28:19","guid":{"rendered":"https:\/\/www.hawaii.edu\/news\/?p=104559"},"modified":"2020-03-13T14:46:24","modified_gmt":"2020-03-14T00:46:24","slug":"ibr-grant","status":"publish","type":"post","link":"https:\/\/www.hawaii.edu\/news\/2019\/10\/09\/ibr-grant\/","title":{"rendered":"$5.3<abbr title=\"million\">M<\/abbr> for world-famous <abbr title=\"University of Hawaii\">UH<\/abbr> reproductive lab"},"content":{"rendered":"<span class=\"span-reading-time rt-reading-time\" style=\"display: block;\"><span class=\"rt-label rt-prefix\">Reading time: <\/span> <span class=\"rt-time\"> 2<\/span> <span class=\"rt-label rt-postfix\">minutes<\/span><\/span><div class=\"responsive-video-wrap-post\"><figure class=\"wp-block-embed wp-block-embed-youtube is-type-video is-provider-youtube epyt-figure\"><div class=\"wp-block-embed__wrapper\"><div class=\"epyt-video-wrapper\"><iframe  id=\"_ytid_28098\"  width=\"620\" height=\"349\"  data-origwidth=\"620\" data-origheight=\"349\" src=\"https:\/\/www.youtube.com\/embed\/C9RguVuL-YU?enablejsapi=1&origin=https:\/\/www.hawaii.edu&rel=0&autoplay=0&cc_load_policy=0&cc_lang_pref=&iv_load_policy=1&loop=0&fs=1&playsinline=0&autohide=2&theme=dark&color=red&controls=1&disablekb=0&\" class=\"__youtube_prefs__  no-lazyload\" title=\"Wiki IBR HD 1080p\"  allow=\"fullscreen; accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen data-no-lazy=\"1\" data-skipgform_ajax_framebjll=\"\"><\/iframe><\/div><\/div><\/figure><\/div>\n<p>The University of <span aria-label=\"Hawaii\">Â鶹´«Ã½<\/span> at M&#257;noa has received a $5.3 million grant to continue research at the laboratory that became world-famous for producing mice and other animals that glow green under ultraviolet light. This grant will allow the John A. Burns School of Medicine <a href=\"https:\/\/www.ibr.hawaii.edu\/\">Institute for Biogenesis Research<\/a> (<abbr>IBR<\/abbr>) to produce transgenic mice for other researchers seeking medical cures at <abbr title=\"University of Hawaii\">UH<\/abbr>.<\/p>\n<p>The mouse and its pups glowed green because jellyfish genes had been inserted into a mouse embryo to demonstrate the lab\u2019s successful technique for inserting <abbr title=\"deoxyribonucleic acid\">DNA<\/abbr> from an unrelated organism into that of another animal. The first green mouse was born, and then she transferred the glowing gene to her pups.<\/p>\n<figure id=\"attachment_104561\" aria-describedby=\"caption-attachment-104561\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-green-mice.jpg\" alt=\"green mouse and babies\" width=\"300\" height=\"300\" class=\"size-full wp-image-104561\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-green-mice.jpg 300w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-green-mice-130x130.jpg 130w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-104561\" class=\"wp-caption-text\">The &ldquo;glowing green mice&rdquo; in the Institute for Biogenesis Research lab in 1999.<\/figcaption><\/figure>\n<p>&ldquo;All along, we\u2019ve been developing new technologies to make us even better,&rdquo; said <strong>Steven Ward<\/strong>, <abbr>IBR<\/abbr> director. &ldquo;With this grant, we&#8217;ll be able to build on our previous 10 years of research to provide genetically altered mice for anybody at <abbr>UH<\/abbr>. These are models that scientists can use for their research\u2014mice with specific diseases or with a certain gene missing or with a gene present so the researchers can see what they can do with it.&rdquo;<\/p>\n<p>Since mice are the closest animals to humans for biological testing, Ward said, making better mouse models allows scientists to advance cures.<\/p>\n<ul>\n<li><a href=\"https:\/\/www.hawaii.edu\/news\/tag\/institute-for-biogenesis-research\/\">Read more about the Institute for Biogenesis Research at <em><abbr>UH<\/abbr> News<\/em><\/a><\/li>\n<\/ul>\n<p>This is the third consecutive five-year funding award the <abbr>IBR<\/abbr> has been selected to receive.<\/p>\n<p>The federal funding from the National Institutes of Health\u2019s National Institute of General Medical Sciences will support collaborations between <abbr>IBR<\/abbr>, part of the <abbr>UH<\/abbr> M&#257;noa <a href=\"https:\/\/jabsom.hawaii.edu\/\">John A. Burns School of Medicine<\/a>, and its reproductive biology departments of <a href=\"https:\/\/jabsom.hawaii.edu\/departments\/abp\/\">anatomy, biochemistry and physiology<\/a> and <a href=\"https:\/\/jabsom.hawaii.edu\/departments\/obgyn\/\">obstetrics, gynecology and women\u2019s health<\/a>.<\/p>\n<p><a href=\"https:\/\/jabsom.hawaii.edu\/5-3m-funding-for-world-famous-reproductive-science-lab-institute-for-biogenesis-research-at-uh-jabsom\/\">For more go to the John A. Burns School of Medicine website.<\/a><\/p>\n<p><em>&#8212;By Tina Shelton<\/em><\/p>\n<figure id=\"attachment_104562\" aria-describedby=\"caption-attachment-104562\" style=\"width: 676px\" class=\"wp-caption alignleft\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-team.jpg\" alt=\"4 people standing in front of I B R lab\" width=\"676\" height=\"381\" class=\"size-full wp-image-104562\" srcset=\"https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-team.jpg 676w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-team-130x73.jpg 130w, https:\/\/www.hawaii.edu\/news\/wp-content\/uploads\/2019\/10\/manoa-jabsom-ibr-team-300x169.jpg 300w\" sizes=\"auto, (max-width: 676px) 100vw, 676px\" \/><figcaption id=\"caption-attachment-104562\" class=\"wp-caption-text\">Institute for Biogenesis Research team from left, Stefan Moisyadi, Michelle Kerklo, Johann Urschitz and William Ward. (Photo credit: Deborah Manog Dimaya)<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The grant will allow the Institute for Biogenesis Research to produce transgenic mice for other researchers seeking medical cures at <abbr>UH<\/abbr>.<\/p>\n","protected":false},"author":16,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[30],"tags":[165,454,31,1363,1286,990,9],"class_list":["post-104559","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research","tag-health","tag-institute-for-biogenesis-research","tag-john-a-burns-school-of-medicine","tag-manoa-research","tag-obstetrics-and-gynecology","tag-reproductive-technology","tag-uh-manoa","entry","has-media"],"aioseo_notices":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/104559","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/users\/16"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/comments?post=104559"}],"version-history":[{"count":7,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/104559\/revisions"}],"predecessor-version":[{"id":113668,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/posts\/104559\/revisions\/113668"}],"wp:attachment":[{"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/media?parent=104559"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/categories?post=104559"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.hawaii.edu\/news\/wp-json\/wp\/v2\/tags?post=104559"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}